HISTORIC MILESTONES ON THE PATH OF THE BIRTH OF MICROSCOPY FROM LIGHT TO ELECTRON MICROSCOPY, AN INTERDISCIPLINARY TECHNIQUE. PART1 LIGHT MICROSCOPY
DOI:
https://doi.org/10.46243/jst.2025.v10.i08.pp16-52Keywords:
History, Microscopy, Electron Microscopy, Review, Nobel Prize, interdisciplinary techniqueAbstract
Microscopes drove theories by providing the tool needed to make advances in many fields of science. Observations through the microscope primarily determined what early scientists thought and advanced science to a great extend as we know it today across many fields of science, becoming a dominating technique. What is captured here are some of the major milestones on the path of the birth of microscopy. The following is covered: The beginning of the light microscope, Early Stereo Microscope development, The Ultra Microscope, Differential interference contrast (DIC). Inverted light Microscope, The Fluorescence microscope, Confocal Microscopy, Confocal Scanning Light Microscope (or ‘CSLM’), Transmission Electron microscope, Scanning Electron Microscope (SEM) and the Environmental scanning electron microscopy (ESEM). With more older manuscripts becoming available digitally, this overview fills in many gaps that exist in some of the previous work, covering a wider history in microscopy. It is also the single most recognised technique, which in its development and application, has produced more Nobel prize laureates than any other technique. Quite a few laurates are born and imbedded in the history of microscopy, some are covered here.
References
De Villiers, G., & Pike, E. R. (2016). “The limits of resolution”. CRC Press. ISBN: 9781498758123
Rubin, M. L. (1986). “Spectacles: Past, present, and future”. Survey of Ophthalmology, 30 (5), 321-327. https://doi.org/10.1016/0039- 6257(86)90064-0
Cashell, G. T. W. (1971). “A Short History of Spectacles”. Proceedings of the Royal Society of Medicine, 64 (10), 1063-1064. https://doi. org/10.1177/003591577106401024
Jaecks, D. (2010). “The Telescope, Its History, Technology, and Future”. In Aestimatio: Critical Reviews in the History of Science (Volume 4) (pp. 175-178). Gorgias Press. https://doi.org/10.31826/9781463232405-
Disney, A. N. (1928). “Origin and development of the microscope”. Journal of the Royal Microscopical Society of London, 26
Leftwich, M. A. (1981). “Historic Microscope Replicas”. Laboratory Medicine, 12 (8), 512-
Van Helden, A., Dupré, S., & van Gent, R. (2010). “The origins of the telescope”. Amsterdam University Press. ISBN: 978-90- 6984-615-6
Haden, R. L. (1939). “The Origin of the Microscope”. Annals of Medical History, 1, 30-
PMID: 33943451; PMCID: PMC7939666
Carpenter, W. B., & Dallinger, W. H. (1901). “The Microscope and Its Revelations”. P. Blackiston’s Sons and Co, 122-125
Borel, P. (1656). “Observationum microscopicarum centuria”. Regis Chrisftianiffimi Medic Ordinareo. (in Spanish). https://www.europeana.eu/item/109/ https hispana_mcu_es_lod_oai_bvpb_mcu_ es_406798_ent0
Gillen, A., & Oliver, D. (2012). “Antony van leeuwenhoek: Creation magnified through his magnificent microscopes”. Faculty Publications and Presentations. https:// digitalcommons.liberty.edu/bio_chem_fac_ pubs/137
Bedini, S. A. (1961). “The optical workshop equipment of giuseppe campani”. Journal of the History of Medicine and Allied Sciences, 16 (1), 18-38. https://www.jstor.org/ stable/24620835
Hooke, R. (1964). “Micrographia: or, Some physiological descriptions of minute bodies made by magnifying glasses”. London: J. Martyn and J. Allestry, (first edition)
Gest, H. (2004). The discovery of microorganisms revisited. ASM News, 70 (6), 269-274
Hellmuth, E., & Wolfgang, M. (2004). “Carl Zeiss in Jena, 1945-1990”. Vandenhoeck & Ruprecht. ISBN: 9783412111960
Uluç, K., Kujoth, G. C., & Başkaya, M. K. (2009). “Operating microscopes: Past, present, and future”. Neurosurgical Focus, 27(3), E4
Henker, O. (1928). “Objective-revolving nose piece for microscopes”. U.S. Patent No. 1,674,041
Bracegirdle, B. (1977). “J. J. Lister and the establishment of histology”. Medical History, 21 (2), 187-191. https://doi.org/10.1017/ S0025727300037716
Gage, S. H. (1920). “Modern dark-field microscopy and the history of its development”. Transactions of the American Microscopical Society, 39(2), 95-141. Figure32. The first commercial ESEM was exhibited in New Orleans by ElectroScan Corporation Stephanus H Coetzee, HISTORIC MILESTONES ON THE PATH OF THE BIRTH OF MICROSCOPY FROM LIGHT TO ELECTRON MICROSCOPY, AN INTERDISCIPLINARY TECHNIQUE. PART1 LIGHT MICROSCOPY
Ortiz Ortega, E., Hosseinian, H., Rosales López, M. J., Rodríguez Vera, A., & Hosseini, S. (2022). “Characterization Techniques for Morphology Analysis”. In Material Characterization Techniques and Applications (pp. 1-45). Springer Singapore
Humphrey, A. T. (1992). “Lord Rayleigh-the last of the great Victorian polymaths”. GEC Review, 7 (3), 167-179
Talbot, W. H. F. (1834). “XLIV. Experiments on light”. The London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science, 5(29), 321-334. https://doi. org/10.1080/14786443408648474
Abbe, E. (1873). “Beiträge zur Theorie des Mikroskops und der mikroskopischen Wahrnehmung”. Archiv für Mikroskopische Anatomie, 9(1), 413-468. https://doi. org/10.1007/BF02956173
von Fraunhofer, J. (1814). “Denkschriften der königlichen akademie der wissenschaften zu München”. Königliche Akademie der Wissenschaften, 193-226
Zeiss, C. (1889). “Optiche Werkstätte” (Vol. 28). Fromannsche Buehdruckerei (Herman Pohle)
Riesenberg, H. (1988). “Handbuch der Mikroskopie”. VEB Verlag Technik, Berlin, 24–107
Broome,B. G. (1992) “Microscope objectives and their evolution to optical disk objectives”. Proc. SPIE 10263, Lens Design: A Critical Review, 102630H; https://doi. org/10.1117/12.131980
Zhang, Y., & Gross, H. (2019). “Systematic design of microscope objectives. Part I: System review and analysis”. Advanced Optical Technologies, 8(5), 313-347. https://doi. org/10.1515/aot-2019-0002
Zei Zeiss, C. (1878). “Description of Professor Abbe’s Apertometer, with Instructions for its Use”. Journal of the Royal Microscopical Society, 1, 19-22. https://doi. org/10.1111/j.1365-2818.1878.tb05895.x
Kepler, J. (1611). “Dioptrice seu demonstratio eorum quae visui & visibilibus propter Conspicilla ita pridem inventa accidunt”. Davidis Franci. Reprint in Latin Kessinger Publishing ISBN 978-1104789428
Malet, A. (2010). “Kepler’s legacy: telescopes and geometrical optics, 1611-1669”. The Origins of the Telescope, 281-300
Gregory, R. L. (1981). “Beyond sense and reason”. Perception, 10 (2), 123-126. https:// doi.org/10.1068/p100123
Wenham, F. H. (1853). “On the Application Binocular vision to the Microscope”. Transactions of the Microscopy Society of London
Beck, R. (2014). “125 years of comparison microscopy-From the ‘camera lucida’ to the Automated Comparison Bridge”. Leica Science Lab
Carl Zeiss. (1902). “Optiche Werkstätte” (32nd ed.). B Vopelius, Jena
Zsigmondy, R. (1909). “Colloids and the Ultramicroscope, a manual of Colloid Chemistry and Ultramicroscopy” (1st ed.). John Wiley & Sons, New York; Chapman & Hall, London
Zsigmondy, R. A. (1926). “Properties of Colloids-Nobel Lecture”. Nobel Lectures, Chemistry 1922-1941. Elsevier Publishing Company
Nomarski, G. (1952). “Interferential polarizing device for study of phase object”. U.S. Patent No. 2,601,175
Smith, F. H. (1952). “Interference Microscope”. U.S. Patent No. 2,601,175
Smith, F. H. (1955). “Microscopic Interferometry”. Research (London), 8, 385-
Nomarski, G. (1960). “Interferential Polarizing Device for Study of Phase Objects”. U.S. Patent, Number 2,924,142. Centre National de la Recherche Scientifique, Paris, France, USA
Allen, R. D., David, G. B., & Nomarski, G. (1969). “The Zeiss-Nomarski Differential Interference Equipment for Transmitted Light Microscopy”. Zeitschrift für wissenschaftliche Mikroskopie, 69, 193-221
2 Malus,E. L. (1809).“ Sur une propriété de la lumière réflécchie par les corps diaphanes.” Arcueil, Mém. De Phys. Ii. 142-58. Stephanus H Coetzee, HISTORIC MILESTONES ON THE PATH OF THE BIRTH OF MICROSCOPY FROM LIGHT TO ELECTRON MICROSCOPY, AN INTERDISCIPLINARY TECHNIQUE. PART1 LIGHT MICROSCOPY
Étienne-Louis Malus, (1811). “Théorie de la double réfraction,” Mémoires présentés à l’Institut par divers savants étrangers, II, 447
Cheshire, P. F. J. (1923). The President’s address: The early history of the polariscope, and the polarizing microscope. Journal of the Royal Microscopical Society, 43(1), 1-18
Touret, J. (2012) “ Le microscope polarisant à l’assaut des montagnes.” Travaux du Comité français d’Histoire de la Géologie, 3ème série (tome 26, 4), pp.67-80. ⟨hal-01065569⟨
Zernicke, F. (1953). “Das Phasenkontrastverfahren bei der mikroskopischen Beobachtung”. Zeitschrift für technische Physik, 16, 454-457
Gundlach, H. (2003). “Frits Zernike and Phase Contrast Microscopy: Celebrating 50 Years of Live Cell Analysis”, Microscopy and Analysis, 5-10
Zeiss (1949). “Großes Forchungsmikroskop LUPAN Beschreinbung und Gebrauchsanweisung”, Optik Carl Zeiss Jena VEB, Waren-Nr 371440
Köhler, A., and Loos, W., (1941). “The Phase Contrast Method and Its Application to Microscopy”, Naturwissenschaften 29, 49-61 translated in Textile Research Journal, 17, 82-95 (Feb. 1947)
Loos, W., (1941). “The Phase Contrast Method in Biological Research”, Klinische Wochenschrift 20, 849-93
Michel, K., (1941). “The Representation of Chromosomes by Means of the Phase Contrast Method”. Naturwissenschaften 29, 61-2
Michel, K., (1943). “Phase Contrast Microscopy,” in Handbuch der wiss. u. angewandten Photographie, Wien, Springer, Supplementary Volume I, chapter entitled “Micrography,” pp. 546-55
Zernike, F. (1955). “How I discovered phase contrast”. Science 121, 345-349
Zeiss C. (1935). “Verfahren zur Erh⟨hung der Lichtdurchl⟨ssigkeit opticher Teile durch Erniedrigung des Brechungsexponenten an dur Grenzfl⟨chen dieser optichen Teile”, Reichstentamt Patentchrift, Nr 685767 Klass 42h, Gruppe 1, Z22836IXa/42h
Paul, H. W. (1985). “From Knowledge to Power: The Rise of the Science Empire in France, 1860- 1939”. Cambridge University Press. https:// doi.org/10.1017/CBO9780511529672
Smith, J. L. (1852). “The inverted microscope-a new form of microscope”. American Journal of Science and Arts, 14, 233-241
A. Nachet. (1886). “Descriptif des instruments de micrograpie constuis par”. Maison Nachet & Fils, Vol 1, Paris
Cassedy, J. H. (1976). “The microscope in American Medical Science, 1840-1860”. History of Science, 67(1), 76-97
Smith, J. L. (1873). “Mineraloggy and Chemistry, Original Researches”. Printed by John P Morton and Company, Loisville, KY
Desch, C. H. (1938). Henry Louis Le Chatelier. 1850-1936. Obituary Notices of Fellows of the Royal Society, 2(6), 251–259. http://www. jstor.org/stable/769060
VEB Carl Zeiss. (1953). “Neophot”. Druckschriften-Nr. CZ 30-675a-1, Jena
Anderson, A. J. O. (1982). “Sahagún: Career and Character”. Florentine Codex: The General History of the Things of New Spain, Introductions and Indices. University of Utah Press
Herschel, J. F. W. (1845). “On a case of superficial colour presented by a homogeneous liquid internally colourless”. Philosophical Transactions of the Royal Society London, 135, 143-145
Stokes, G. G. (1852). “On the change of refrangibility of light”. Philosophical Transactions of the Royal Society of London, 142, 463-562
Garfield, S. (2001). “Mauve: How One Man Invented a Color that Changed the World”. W. W. Norton & Company. ISBN: 978- 0393020052
Helmholtz, H. (1874). “Die theoretischen Grenzen für die Leistungsfähigkeit der Mikroskope”. Annalen der Physik, 557-584
Ehrlich P. (1882). “Ueber provocirte fluorescenzerscheinungen am auge”. Dtsch Med Wochenschr. 8:21, Stephanus H Coetzee, HISTORIC MILESTONES ON THE PATH OF THE BIRTH OF MICROSCOPY FROM LIGHT TO ELECTRON MICROSCOPY, AN INTERDISCIPLINARY TECHNIQUE. PART1 LIGHT MICROSCOPY doi:10.1055/s-0029-1196319
McClure, D. M., (1953). “The Development of Fluorescence Microscopy for Tubercle Bacilli and its Use as an Adjunct to Histological Routine”., Journal of Clinical Pathology; Vol. 6, Iss. 4, 273. DOI:10.1136/jcp.6.4.273
Novotny, H. R., & Alvis, D. L. (1961). “A method of photographing fluorescence in circulating blood in the human retina”. Circulation, 24, 82-86
Same, P. J. (1993). “Landmarks in the Historical Development of Fluorescein Angiography”. Journal of Ophthalmic Photography, 15 (1), 17-23
Köhler R, (1893). “Ein neues Beleuchtungsverfahren für mikrophotographische Zwecke”. Zeitschrift für wissenschaftliche Mikroskopie und für Mikroskopische Technik. 10 (4): 433–440
E. Lommel (1875). “Uber Fluorescenz”, Annalen der Physik (1871-1880)
Harvey, E. N. (1957). A history of luminescence from the earliest times until 1900. Memoirs of the American Philosophical Society, v. 44
Masters, B. R. (2008). History of the optical microscope in cell biology and medicine. Encyclopedia of Life Sciences, 8
Heimstadt, O. (1911). “Das Fluoreszenzmikroskop”. Zeitschrift für wissenschaftliche Mikroskopie, 28, 330-337
Lehmann, H. (1913). “Das Lumineszenz-Mikroskop, seine Grundlagen und seine Anwendungen“. Zeitschr. Wissensch. Mikrosk. 30, 418–470
Sluder, G., & Nordberg, J. J. (2013). “Microscope Basics”. In Methods in Cell Biology (Vol. 114, pp. 1-10). Academic Press. ISBN: 9780124077614 https://doi.org/10.1016/ B978-0-12-407761-4.00001-4
Reichert, K. (1911). “Das Fluoreszenzmikroskop”. Physikalische Zeitschrift, 12, 1010-1011
Coons, A. H, Creech, H. J., Jones, N. R., & Berliner, E. (1942). “The Demonstration of pneumococcal antigen in tissues by the use of fluorescent antibody”. Journal of Immunology, 45, 159-170
Fischer, J. G. (1911). “Fluorescence microscopy”. Zeitschrift für wissenschaftliche Mikroskopie, 28. - Garrison & Morton No. 269.2
Davidson, L., & Keller, R. (2001). “Basics of a Light Microscopy Imaging System and Its Application in Biology”. Methods in Cellular Imaging. 1-45. Springer. https://doi. org/10.1007/978-1-4614-7513-2_4
Ellinger, P. H., & Hirt, A. (1929). “Mikroskopische beobachtungen an lebenden organen mit demonstrationen (Intravitalmikroskopie)”. Archiv für Experimentelle Pathologie und Pharmakologie, 147(1-3), 63-63. https://doi. org/10.1007/BF01946036
Burrichter, E. (1953). “Beiträge zur Beurteilung von Böden auf Grund fluoreszenzmikroskopischer Untersuchung ihrer Mikroflora”. Zeitschrift für Pflanzenernährung, Düngung, Bodenkunde, 63(2), 154-171. https://doi.org/10.1002/ jpln.19530630206
Ploem, J. S. (1967). “The use of a vertical illuminator with interchangeable dichroic mirrors for fluorescence microscopy with incidental light”. Zeitschrift für Wissenschaftliche Mikroskopie und Mikroskopische Technik, 68 (3), 129-142
Minsky, M. (1961). “Minsky’s microscopy apparatus”. US Patent 3,013,467
Patil-Takbhate, B., Takbhate, R., Khopkar-Kale, P., & Tripathy, S. (2024). “Marvin minsky: The visionary behind the confocal microscope and the father of artificial intelligence”. Cureus. https://doi.org/10.7759/cureus.68434
Claxton, N. S., Fellers, T. J., & Davidson, M. W. (2006). “Laser scanning confocal microscopy”. Encyclopedia of Medical Devices and Instrumentation, 21 (1), 1-37
Winston, P. (2016) “Marvin L. Minsky” (1927--2016). Nature, 530, 282. https://doi. org/10.1038/530282a
Airy, G. B. (1835). “On the diffraction of an object-glass with circular aperture”. Transactions of the Cambridge Philosophical Society, 5, 283-291
Petran, M., & Hardravsky, M. (1970). “Method and arrangement for improving the Stephanus H Coetzee, HISTORIC MILESTONES ON THE PATH OF THE BIRTH OF MICROSCOPY FROM LIGHT TO ELECTRON MICROSCOPY, AN INTERDISCIPLINARY TECHNIQUE. PART1 LIGHT MICROSCOPY resolving power and contrast”. U.S. Patent No. 3,517,980
Petran, M., Hardravsky, M., & Maly, M. (1990). “Arrangement for illumination and scanning of an object by means of a scanning disc similar to a Nipkow disk”. U.S. Patent No. 4,917,478
Egger, M. D., & Petráň, M. (1967). “New reflected-light microscope for viewing unstained brain and ganglion cells”. Science, 157 (3786), 305-307. https://doi. org/10.1126/science.157.3786.305
Goldstein, S. R. (1987). “Confocal laser scanning microscope with no moving parts”. U.S. Patent No. 4,827,125
Davidovits, P., & Egger, M. D. (1969). “Scanning laser microscope”. Nature, 223 (5208), 831-
https://doi.org/10.1038/223831a0
Sheppard, C. J. R., & Choudhury, A. (1977). “Image formation in the scanning microscope”. Optica Acta: International Journal of Optics, 24 (10), 1051-1073
Brakenhoff, G. J., Blom, P., & Barends, P. (1979). “Confocal Scanning Light Microscopy with High Aperture Immersion Lenses”. Journal of Microscopy, 117, 219-232
Pawley, J. B. (1995). “Handbook of biological confocal microscopy” (2nd ed.). Plenum Press. ISBN: 0-306-448262
Thomson, J. J. (1897). “Cathode Rays”. Philosophical Magazine, 44(269), 293-316
Thomson, J. J. (1906). “In recognition of the great merits of his theoretical and experimental investigations on the conduction of electricity by gases”. NobelPrize.org. https://www. nobelprize.org/prizes/physics/1906/ summary
Thomas, J. M. (2006). “J. J. Thomson: Winner of the Nobel Prize for Physics 1906”. Angewandte Chemie International Edition, 45 (41), 6797-6800
Bohr, N. (1913). “On the constitution of atoms and molecules”. Philosophical Magazine Series 6, 26, 1-25
de Broglie, L. (1924). XXXV. “A tentative theory of light quanta”. The London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science, 47(278), 446-458. https://doi. org/10.1080/14786442408634378
de Broglie, L. V. (1929). “For his discovery of the wave nature of electrons”. NobelPrize. org. https://www.nobelprize.org/prizes/ physics/1929/summary
Davisson, C., & Germer, L. H. (1927). “The Scattering of Electrons by a Single Crystal of Nickel”. Nature, 119(2998), 558. https://doi. org/10.1038/119558a0 S2CID: 4104602
Davisson, C., & Germer, L. H. (1927). “Diffraction of Electrons by a Crystal of Nickel”. Physical Review, 30(6), 705-740. https://doi. org/10.1103/PhysRev.30.705 ISSN: 0031- 899X
Davisson, C. J., & Thomson, G. P. (1937). “For their experimental discovery of the diffraction of electrons by crystals”. NobelPrize.org. https:// www.nobelprize.org/prizes/physics/1937/ summary
Busch, H. (1926). “Berechnung der Bahn von Kathodenstrahlen im axialsymmetrischen elektromagnetischen Felde”. Annalen der Physik, 386(25), 974-993. https://doi. org/10.1002/andp.19263862507
De Broglie, L. (1923). “Onde et quanta”. Compte Rendus, 177, 507-510
Kracklauer, A. F. (1974). “On the Imaginable content of De Broglie waves”. Scientia (Milano), 109, 111-120
Gabor, D. (1971). “For his invention and development of the holographic method”. NobelPrize.org. https://www.nobelprize.org/ prizes/physics/1971/summary
Ruska, H., von Borries, B., & Ruska, E. (1940). “Die Bedeutung der Übermikroskopie für die Virusforschung”. Archiv für die gesamte Virusforschung, 1, 155-169
Ruska, E. (1987). “The development of the electron microscope and of electron microscopy”. Reviews of Modern Physics, 59, 627. https://doi.org/10.1103/ RevModPhys.59.627
Ruska, E. (1986). “For his development of the electron microscope”. NobelPrize.org. https:// www.nobelprize.org/prizes/physics/1986/ summary/
Knoll, M. (1929). “Vorrichtung zur Stephanus H Coetzee, HISTORIC MILESTONES ON THE PATH OF THE BIRTH OF MICROSCOPY FROM LIGHT TO ELECTRON MICROSCOPY, AN INTERDISCIPLINARY TECHNIQUE. PART1 LIGHT MICROSCOPY Konzentrierung des Elektronenstrahls eines Kathoden-strahloszillographen”. German Patent No. 690809. Granted on 11 April 1940
Ruska, E., & Knoll, M. (1931). “Die magnetische Sammelspule für schnelle Elektronenstrahlen”. Zeitschrift für technische Physik, 12, 389-400
Knoll, M., & Ruska, E. (1932). “Das Elektronenmikroskop”. Zeitschrift für Physik, 78, 318-339
Gelderblom, H. R., & Kruger, D. H. (2014). “Helmut Ruska (1908-1973): His Role in the Evolution of Electron Microscopy in the Life Sciences, and Especially Virology”. Advances in Imaging and Electron Physics, 182, 1-94. ISSN: 1076-5670 ISBN: 9780128001462
Frank, J. (2019). “The Electron Microscope-from a sketch in 1931 to reality”. Frank Lab News
Schimmel, G. (1996). “The History of the German Society for Electron Microscopy”. Advances in Imaging and Electron Physics, 96, 149-170. ISBN: 9780120147380
Ruska, E. (1988). “The development of the electron microscope and of electron microscopy”. EMSA Bulletin, 18 (2), 53-61
Hawkes, P. (2001). “A souvenir of Philips electron microscopes”. Advances in Imaging and Electron Physics, 115, 355-361. ISBN: 9780120147571 https://doi.org/10.1016/ S1076-5670(01)80098-7
Yoshimura, N. (2014). “History of JEOL Electron Microscopes”. In Historical Evolution Toward Achieving Ultrahigh Vacuum in JEOL Electron Microscopes (pp. 11-23)
Porter, K. R., & Blum, J. (1953). “A Study in Microtomey for Electron Microscopy”. Anatomical Record, 117, 685-710. https:// doi.org/10
Pade, G. E. (1952). “A study of fixation for electron microscopy”. Journal of Experimental Medicine, 95(3), 285-298. PMID: 14927794; PMCID: PMC2212069
Claude, A., de Duve, C., & Palade, G. E. (1974). “For their discoveries concerning the structural and functional organization of the cell”. NobelPrize.org
Stintzing H. (19290 Verfahren und Einrichtung zum automatischen Nachweiss, Messung und Zählung von Einzellteilchen beliebiger Art, Form und Grösse. German patent No 485155 (1929a)
Stintzing, H. (1929). “Einrichtung zum automatischen Nachweis, Messung und Zählung von Einzelteilchen beliebiger Art, Form und Grösse nach Patent 485155, insbesondere zur Erzeugung sehr enger Strahlenbündel”. German Patent No. 485156
Knoll, M. (1935). “Aufladepotentiel und Sekundäremission elektronenbestrahlter Körper”. Zeitschrift für technische Physik, 16, 467-475
von Ardenne, M. (1937). “Improvements in electron microscopes”. British Patent No. 511204. Convention date (Germany) 18 Feb 1937
von Ardenne, M. (1938). “Das Elektronen-Rastermikroskop. Theoretische Grundlagen”. Zeitschrift für Physik, 109, 553-572
von Ardenne, M. (1938). “Das Elektronen-Rastermikroskop Praktische Ausführung”. Zeitschrift für technische Physik, 19, 407-416
Zworykin, V. K. (1942). “New Scanning Electron Microscope revealed to Engineers”. Radio-Craft, Special Radio War number, September. Ed. Gernsback H. Radcraft Publications, Inc
Oatley, C. W. (1982). “The early history of the scanning electron microscope”. Journal of Applied Physics, 53 (2)
Baxter A.S., (1949) “Detection and analysis of low energy disintegration particles”. PhD Diss., Cambridge U
McMullan, D. (1952). “Investigations relating to the design of electron microscopes” [Doctoral dissertation]. Cambridge University
Smith, K. C. A., Wells, O. C., & McMullan, D. (2008). “The fiftieth anniversary of the first applications of the scanning electron microscope in materials research”. Physics Procedia, 3-12. http://dx.doi.org/10.1016/j. phpro.2008.07.073
McMullan, D. (1953). “An improved scanning electron microscope for opaque specimens”. Proc. Inst. Electr. Engrs. 100, Part II, 245–259. Stephanus H Coetzee, HISTORIC MILESTONES ON THE PATH OF THE BIRTH OF MICROSCOPY FROM LIGHT TO ELECTRON MICROSCOPY, AN INTERDISCIPLINARY TECHNIQUE. PART1 LIGHT MICROSCOPY
McMullan, D. (2008). “The Early Development of the Scanning Electron Microscope”. In Biological Low-Voltage Scanning Electron Microscopy. Springer. https://doi. org/10.1007/978-0-387-72972-5_1
Oatley, C. W., Nixon W. C., & Pease R. F. W. (1965). “Scanning electron microscopy”. Adv. Electron. Electron Phys. 21, 181–247
Everhart T. E. & R Thornley F. M. (1960) “Wide-band detector for micro-microampere low-energy electron currents “ J. Sci. Instrum. 37 246
Goldstein, J., Newbury, D.E., Joy, D.C., et al. (2003) “Scanning Electron Microscopy and X-Ray Microanalysis”. Kluwer Academic/ Plenum Publishers, New York, 550
Inada, H., Kakibayashi, H., Isakozawa, S., Hashimoto, T., Yaguchi, T., & Nakamura, K. (2009). “Hitachi’s Development of Cold-Field Emission Scanning Transmission Electron Microscopes”. Advances in Imaging and Electron Physics, 159, 123-186. ISBN: 9780123749864 https://doi.org/10.1016/ S1076-5670(09)59004-0
Castaing, R. (1951). “Application of electron probes to local chemical and crystallographic analysis” [Doctoral dissertation]. University of Paris
Cosslett, V. E., & Duncumb, P. (1956). “Microanalysis by a flying-spot X-ray method”. Nature, 177, 1172-1173
Duncumb, P., & Cosslett, V. E. (1957). “A scanning microscope for X-ray emission pictures”. In X-ray Microscopy and Microradiography. 374-380. Academic Press
Camus, P., & Nylese, T. (2017). “More Than 50 Years of Influence On Microanalysis”. Microscopy and Microanalysis, 23(S1), 1020-1021. https://doi.org/10.1017/ S1431927617005761
Fitzgerald, R., Keil, K., & Heinrich, K. F. (1968). “Solid-state energy-dispersion spectrometer for electron-microprobe x-ray analysis”. Science, 159 (3814), 528-530. https://doi. org/10.1126/science.159.3814.528
Friel, J. J., & Lyman, C. E. (2006). “X-ray mapping in electron-beam instruments”. Microscopy and Microanalysis, 12 (1), 2-25
Danilatos, G. D., & Postle, R. (1982). “The environmental scanning microscope and its applications”. Scanning Electron Microscopy, 1, 1-16
Pfefferkorn, G. E., Gruter, H., & Pfatusch, M. (1972). “Observations on the prevention of specimen charging”. Scanning Electron Microscopy, 147-152
Robinson, V. N. E. (1975). “Wet stage modification to a scanning electron microscope”. Journal of Microscopy, 103, 71-
Robinson, V. N. E. (1975). “The elimination of charging artifacts in the scanning electron microscope”. Journal of Physics E, 8, 638-640
Danilatos, G. D., & Robinson, V. N. E. (1979). “Principles of Scanning Electron Microscopy at High Specimen Chamber Pressures”. Scanning, 2, 72-82
Danilatos, G. D. (1983). “Gaseous detector device for an environmental electron probe microanalyzer”. *Research Disclosure No. 23311*, 284
Danilatos, G. D. (1983). “A gaseous detector device for an environmental SEM”. Micron and Microscopica Acta, 14, 307-319
Danilatos, G. D. (1986). “Method and Apparatus for an Atmospheric Scanning electron Microscope”. U.S. Patent No. 4,596,928
Danilatos, G. D. (1989). “Multipurpose gaseous detector device for electron microscope “. U.S. Patent No. 4,992,662
Danilatos, X. G. D. (1993). “Introduction to the ESEM instrument”. Microscopy Research and Technique, 25, 354-361
Bogner, A., Jouneau, P. H., Thollet, G., Basset, D., & Gauthier, C. (2007). “A History of Scanning Electron Microscopy Developments: Towards ‘Wet-STEM’ Imaging”. Micron, 38, 390-401. https://doi.org/10.1016/j. micron.2006.06.008
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