Inhibition of Proliferation of K-562 Human Blood Cancer Cell Due To Opuntia Elatior Fruit Extract
DOI:
https://doi.org/10.46243/jst.2021.v06.i04.pp32-38Keywords:
Opuntia elatior,, MTT, Flow cytometry, LC-MS/MSAbstract
The ethanolic extract of Opuntia elatior was studied for anticancer potential against human blood cancer cell line K-562. The cytotoxicity of ethanolic extract was analyzed, using MTT assay and flow cytometric analysis. It was noticed that IC50 value of Opunria elatior curde extract was 74.32 µl/ml showing its cytotoxicity in the human blood cancer cell line by using MTT assay. The flow cytometry evaluation exhibits cell arrested in G2/M and S phases. Cell arrested due to Opuntia elatior extract shows higher than positive control Cisplatin. Thus Opuntia elatior fruit extract might be used as potent source of anticancerous compound against human blood cancer.
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