Machine Learning-based Detection of Malaria Infection through Blood Sample Analysis

Authors

  • N. Teja
  • K. Vyshnavi
  • M. Pavana Sri
  • K. Bharathi

DOI:

https://doi.org/10.46243/jst.2023.v8.i12.pp185-198

Keywords:

malaria infection, blood samples, machine learning, epidemiological.

Abstract

Malaria, a life-threatening disease caused by Plasmodium parasites transmitted through infected mosquitoes, remains a significant public health concern in many regions worldwide. Early and accurate detection of malaria infection is crucial for timely treatment and disease management. The automated malaria detection system can be integrated into portable diagnostic devices, enabling healthcare professionals to perform rapid and accurate malaria tests in remote or resource-limited settings. The system can assist researchers and health organizations in tracking malaria prevalence and monitoring its spread, contributing to epidemiological studies and efficient resource allocation. Conventional methods for malaria detection involve manual examination of blood smears under a microscope by trained technicians. Although reliable, this process is time-consuming, labor-intensive, and dependent on the expertise of the microscopist. The regression-based examination of blood smears introduces the potential for errors, leading to false-negative or false-positive results. In recent years, machine learning-based approaches have shown promising results in automating the detection of malaria parasites through blood sample analysis. This work presents an advanced machine learning-based method for the automated detection of malaria infection, leveraging image processing techniques to achieve high accuracy and efficiency.

References

WHO? World Malaria Report 2022. Available online: https://www.who.int/teams/globalmalaria-programme/reports/world-malariareport-2022 (accessed on 1 March 2023)

WHO? World Malaria Report 2021: An In-Depth Update on Global and Regional Malaria Data and Trends. Available online: https://www.who. int/teams/global-malaria-programme/reports/ world-malaria-report-2021 (accessed on 1 September 2022)

Yang, F.; Poostchi, M.; Yu, H.; Zhou, Z.; Silamut, K.; Yu, J.; Maude, R.J.; Jaeger, S.; Antani, S. Deep learning for smartphone-based malaria parasite detection in thick blood smears. IEEE J. Biomed. Health Inform. 2019, 24, 1427–1438

World Health Organization. Malaria Microscopy Quality Assurance Manual, 2nd ed.; World Health Organization: Geneva, Switzerland, 2016; Available online: https://www.who.int/ docs/default-source/documents/publications/ gmp/malaria-microscopy-quality-assurancemanual.pdf (accessed on 2 March 2023)

Rawat, W.; Wang, Z. Deep convolutional neural networks for image classification: A comprehensive review. Neural Comput. 2017, 29, 2352–2449

Colubri, A.; Silver, T.; Fradet, T.; Retzepi, K.; Fry, B.; Sabeti, P. Transforming clinical data into actionable prognosis models: Machine-learning framework and field-deployable app to predict outcome of Ebola patients. PLoS Negl. Trop. Dis. 2016, 10, e0004549. [Green Version]

Smith, K.P.; Kirby, J.E. Image analysis and artificial intelligence in infectious disease diagnostics. Clin. Microbiol. Infect. 2020, 26, 1318–1323

Das, D.K.; Ghosh, M.; Pal, M.; Maiti, A.K.; Chakraborty, C. Machine learning approach for automated screening of malaria parasite using light microscopic images. Micron 2013, 45, 97–

Bibin, D.; Nair, M.S.; Punitha, P. Malaria parasite detection from peripheral blood smear images using deep belief networks. IEEE Access 2017, 5, 9099–9108

Gopakumar, G.P.; Swetha, M.; Sai Siva, G.; Sai Subrahmanyam, G.R.K. Convolutional neural network-based malaria diagnosis from focus stack of blood smear images acquired using custom-built slide scanner. J. Biophotonics 2018, 11, e201700003

Dandekar, R.; Rackauckas, C.; Barbastathis, G. A machine learning-aided global diagnostic and comparative tool to assess effect of quarantine control in COVID-19 spread. Patterns 2020, 1, 100145

Baldominos, A.; Puello, A.; Oğul, H.; Aşuroğlu, T.; Colomo-Palacios, R. Predicting infections using computational intelligence–a systematic review. IEEE Access 2020, 8, 31083–31102. N. Teja, K. Vyshnavi, M. Pavana Sri, K. Bharathi: Machine Learning-based Detection of Malaria Infection through Blood Sample Analysis

O’Shea, K.; Nash, R. An introduction to convolutional neural networks. arXiv 2015, arXiv:1511.08458

Sadeghi-Tehran, P.; Angelov, P.; Virlet, N.; Hawkesford, M.J. Scalable database indexing and fast image retrieval based on deep learning and hierarchically nested structure applied to remote sensing and plant biology. J. Imaging 2019, 5, 33. [Green Version]

Wu, J. Introduction to Convolutional Neural Networks; National Key Lab for Novel Software Technology, Nanjing University: Nanjing, China, 2017; Volume 5, p. 495. [Google Scholar]

Sen, O.; Keles, H.Y. A Hierarchical Approach to Remote Sensing Scene Classification. PFG–J. Photogramm. Remote Sens. Geoinf. Sci. 2020, 90, 161–175

Alzubaidi, L.; Zhang, J.; Humaidi, A.J.; Al-Dujaili, A.; Duan, Y.; Al-Shamma, O.; Santamaría, J.; Fadhel, M.A.; Al-Amidie, M.; Farhan, L. Review of deep learning: Concepts, CNN architectures, challenges, applications, future directions. J. Big Data 2021, 8, 53

Published

2023-12-13

How to Cite

N. Teja, K. Vyshnavi, M. Pavana Sri, & K. Bharathi. (2023). Machine Learning-based Detection of Malaria Infection through Blood Sample Analysis. Journal of Science & Technology , 8(12), 185–198. https://doi.org/10.46243/jst.2023.v8.i12.pp185-198